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KMID : 1149520220060020033
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Cardiovasclar Imaging Asia
2022 Volume.6 No. 2 p.33 ~ p.40
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Assessment of Left Ventricular Function and Regional Wall Motion by 256-Slice Dual-Source Coronary CT Angiography: A Comparison With 2D Transthoracic Echocardiography
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Thuy Lien Le Thi
Khoi Viet Nguyen
Van Hoa Hoang
Bao Ngoc Phung
Ngoc Trang Nguyen
Kim Thoa Vu Thi
Cong Tien Nguyen
Anh Phuong Phan
Minh Thong Pham
Dang Luu Vu
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Abstract
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Purpose: To compare left ventricular (LV) function, ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), and regional wall motion analyzed in 256-slice dual-source coronary CT angiography (DSCT) with 2D transthoracic echocardiography (TTE).
Materials and Methods: One hundred twelve patients suspected of coronary artery disease underwent DSCT and 2D-TTE within one week for LVEF, EDV, and ESV. The correlation between DSCT and 2D-TTE measurements was analyzed through linear regression and Bland-Altman analysis. Regional wall motion was visually scored with a 3-point scale (1, normal; 2, hypokinesia; 3, dysphagia, akinesia).
Results: Average LVEF at 66.45%±1.27% (range 23%?85%) as determined on DSCT compared with 66.09%±1.01% (range 25%?84%) on 2D-TTE. LVEF exhibited a good correlation between DSCT and 2D-TTE (r=0.715; p<0.001). Good correlations between DSCT and 2D-TTE were demonstrated for LVEDV (r=0.732; p<0.001) and LVESV (r=0.841; p<0.001). Mean differences (±SD) of 1.78±24.10 mL (p<0.05) and 0.77±13.70 mL (p<0.05) were observed between DSCT and 2D-TTE for LVEDV and LVESV, respectively. LVEF was slightly overestimated with DSCT (0.52%±9.59%; p<0.05). Although the LVEF values calculated by DSCT and 2D-TTE were similar, EDV and ESV from DSCT were statistically higher than those from 2D-TTE (p<0.05). Agreement between DSCT and 2D-TTE in regional wall motion was 96.4%, κ=0.840.
Conclusion: DSCT can provide comparable results to those using 2D-TTE for LV function (EF, EDV, and ESV) and regional wall motion assessment in a heterogeneous population.
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KEYWORD
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Dual-source CT, Coronary artery disease, Left ventricular function, Echocardiography, Radiation
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